Alarming projections indicate that by 2030, colorectal cancer could become the leading cause of cancer-related deaths among young adults. Recent research has focused on understanding the factors driving this increase, particularly in individuals under 40.

The Role of Escherichia coli and Colibactin

Scientists have identified a specific strain of Escherichia coli in patients under 40 diagnosed with colorectal cancer. This bacterium, commonly found in the digestive tract, possesses a unique characteristic: it produces a toxin called colibactin.

colibactin’s impact is notable.It will alter DNA and promote the occurrence of colorectal cancers. This suggests a direct link between this bacterial toxin and the development of this type of cancer.

oxygen, Sugar, and the Intestinal Habitat

The activity of this E. coli strain is influenced by two key factors: sugar and oxygen. The intestine naturally has varying levels of oxygen, with some areas being highly oxygenated and others, like the intestinal wall, having lower oxygen levels.

The problem arises when oxygen is scarce. In these low-oxygen environments,the bacteria can develop. It thus produces toxin and causes cancer. This highlights the importance of understanding how to maintain a healthy balance within the gut.

Combating the Risk: Oxygenation and Physical Activity

Researchers are exploring methods to increase oxygen levels in the intestine. While direct methods are still under investigation, one proven strategy is physical activity.

When you move, when you play sports, you increase the infusion of the intestine and that is in that sport protects from colorectal cancer to such an extent that sedentary lifestyle is a risk factor for this type of cancer. Regular exercise promotes better oxygenation and reduces the risk.

The impact of Sugar on the Microbiota

Sugar consumption, particularly during childhood, plays a significant role in the proliferation of toxin-producing E.coli. Sugar consumption, especially in childhood, contributes to the proliferation of Escherichia coli which will produce toxin. So in fact,the sugar disrupts our microbiota.

While overall sugar consumption has remained relatively stable since the 1980s, the source of sugar has changed. The rise of ultra-processed foods, packed with additives and unhealthy sugars like glucose and fructose, is a major concern. these foods disturbs the microbiota and increases the risk of colorectal cancer.

Protective Foods: A Dietary Defense

Certain food groups offer protection against colorectal cancer:

• Fruits and Vegetables: Rich in antioxidants, especially colorful varieties. The more vibrant the color, the higher the concentration of vitamins and antioxidants.
• Fiber-Rich Foods: Legumes and whole-grain products promote healthy digestion and gut flora.
• Dairy products: Despite some criticism, dairy products are beneficial.Children should consume three servings daily, and adults two, as calcium protects against colorectal cancer.